60S ribosomal protein L31 is a protein that in humans is encoded by the RPL31 gene.
Function
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L31E family of ribosomal proteins. It is located in the cytoplasm. Higher levels of expression of this gene in familial adenomatous polyps compared to matched normal tissues have been observed. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Interactions
RPL31 has been shown to interact with BRCA1.
References
External links
- Human RPL31 genome location and RPL31 gene details page in the UCSC Genome Browser.
- Overview of all the structural information available in the PDB for UniProt: P62899 (Human 60S ribosomal protein L31) at the PDBe-KB.
Further reading
